Gunmen have opened fire in a downtown bar in the tourist district of Guadalajara, Mexico, killing six people and wounding another 37

The suspects also threw a grenade into the bar after the shooting. A Colombian and a Venezuelan are among the possible victims of the attack. Violence has escalated in Guadalajara, an economic and tourist hub in Mexico, which recently has seen a spate of killings and road blockades by organized criminals. The wave of violence may be related to the dispute between drug cartels after the death of alleged cartel member Ignacio Nacho Coronel, who was killed in July 2010. It has cast a pall on Guadalajara, picked to host the Pan American Games in October 2011.